Hydrochloric Acid → HCID 178479523, compound

Participants

Reaction Steps

Aminoguanidine hydrogencarbonate (45 mg, 0.33 mmol) was dissolved in 2 ml of 1 N HCl. A solution of N-(3-oxo-2,3-dihydro-1H-inden-5-yl)naphthalene-2-sulfonamide (100 mg, 0.30 mmol) in methanol (2 ml) was added and the mixture was heated to reflux for 1 hour. Then the mixture was concentrated in vacuo and the precipitated salt was crystallized from acetonitrile to give 48 mg (36%) of 2-{6-[(2-naphthylsulfonyl)amino]-2,3-dihydro-1H-inden-1-ylidene}hydrazinecarboximidamide hydrochloride.

Provenance & Evidence