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HRID1096206

反应详情

EQUATION

反应方程式

HRID 1096206 的结构方程式

REACTANTS

反应物

2
反应SMILES：Cl.O[C@@H]1CNCCC12CC2
HCID44541812

未命名化合物

2 次

反应SMILES：COC(=O)[C@H](CC=O)N1CCN(c2cccc(C(F)(F)F)c2)CCC1=O
HCID86638381

未命名化合物

PRODUCTS

产物

1
反应SMILES：COC(=O)[C@H](CCN1CCC2(CC2)[C@H](O)C1)N1CCN(c2cccc(C(F)(F)F)c2)CCC1=O
HCID59159284

未命名化合物

收率 70%

PROCEDURE

实验过程

In analogy to the procedure described in example 1K, (S)-4-oxo-2-[7-oxo-4-(3-trifluoromethyl-phenyl)-[1,4]diazepan-1-yl]-butyric acid methyl ester and (S)-6-aza-spiro[2.5]octan-4-ol hydrochloride (intermediate 2) gave the pure title compound in 70% yield as light yellow foam. MS: 484.4 (MH+).