HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium borohydride → HCID 59159273, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium borohydride | HCID 4148881 | — |
| Reactant | HCID 59159251 | HCID 59159251 | — |
| Product | HCID 59159273 | HCID 59159273 | 75% |
Reaction Steps
In analogy to the procedure described in example 2, (S)-4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-2-[7-oxo-4-(4-trifluoromethyl-phenyl)-[1,4]diazepan-1-yl]-butyric acid methyl ester and LiBH4 gave the title compound in 75% yield as a white foam. MS: 456.3 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08138175B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-11d7ba4959d246cb9430b20e27ceb519 |
| Source note | uspto-grants-2012_03 |