Piperidine, 1-(3-chloropropyl)- → HCID 66783287, compound

HRID 1096245Notes

Reaction equation

HRID 1096245 reaction equation
[CH2:1]([O:8][C:9]([N:11]1[CH2:17][CH2:16][C:15](=[O:18])[NH:14][CH2:13][C@H:12]1[CH3:19])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:21][CH2:22][CH2:23][N:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>>[CH2:1]([O:8][C:9]([N:11]1[CH2:17][CH2:16][C:15](=[O:18])[N:14]([CH2:21][CH2:22][CH2:23][N:24]2[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]2)[CH2:13][C@H:12]1[CH3:19])=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 79625Piperidine, 1-(3-chloropropyl)-HCID 66783129HCID 66783129, compound

Product 1

HCID 66783287HCID 66783287, compound

Procedure

The title compound could be prepared from (R)-2-methyl-5-oxo-[1,4]diazepane-1-carboxylic acid benzyl ester and 1-(3-chloropropyl)piperidine in analogy to example 33A. MS: 388.3 (MH+).

Sources & evidence

ORD record
ord-e8453f3e4566442fa3b397faba499df3
Source dataset
uspto-grants-2012_03
Patent number
US08138175B2

Reaction notes

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