Benzene, 1-iodo-2-(trifluoromethyl)- → HCID 59159298, compound

HRID 1096247Notes

Reaction equation

HRID 1096247 reaction equation
[CH3:1][C@@H:2]1[CH2:8][N:7]([CH2:9][CH2:10][CH2:11][N:12]2[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]2)[C:6](=[O:18])[CH2:5][CH2:4][NH:3]1.I[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[C:26]([F:29])([F:28])[F:27]>>[CH3:1][C@@H:2]1[CH2:8][N:7]([CH2:9][CH2:10][CH2:11][N:12]2[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]2)[C:6](=[O:18])[CH2:5][CH2:4][N:3]1[C:25]1[CH:24]=[CH:23][CH:22]=[C:21]([C:26]([F:29])([F:28])[F:27])[CH:20]=1

Participants

3

Reactant 2

HCID 67957Benzene, 1-iodo-2-(trifluoromethyl)-HCID 66783071HCID 66783071, compound

Product 1

HCID 59159298HCID 59159298, compound

Procedure

The title compound was prepared from (R)-2-methyl-4-(3-piperidin-1-yl-propyl)-[1,4]diazepan-5-one and iodobenzotrifluoride in analogy to example 33. MS: 398.3 (MH+).

Sources & evidence

ORD record
ord-9df9cefa11e545e3a6f714841d12221a
Source dataset
uspto-grants-2012_03
Patent number
US08138175B2

Reaction notes

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