Lithium borohydride → HCID 66783028, compound

Participants

Reaction Steps

In analogy to the procedure described in example 2, (S)-2-[(R)-4-(3,4-dichloro-phenyl)-3-methyl-7-oxo-[1,4]diazepan-1-yl]-4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-butyric acid methyl ester (example 65) and LiBH4 gave the title compound in 61% yield as white solid. MS: 470.2 (MH+, 2Cl).

Provenance & Evidence