HCID 11571812, compound → 3-(1,3-Thiazol-2-yl)propan-1-ol

HRID 1096826Notes

Reaction equation

HRID 1096826 reaction equation
[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[C:6]#[C:7][CH2:8][OH:9]>CCO.[Pd]>[S:1]1[CH:5]=[CH:4][N:3]=[C:2]1[CH2:6][CH2:7][CH2:8][OH:9]

Participants

4

Reactant 1

HCID 11571812HCID 11571812, compound

Product 1

HCID 178291513-(1,3-Thiazol-2-yl)propan-1-ol

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Pd on charcoal (0.5 g) was added to a sol. of 3-thiazol-2-yl-prop-2-yn-1-ol (2.31 g, 16.6 mmol) in EtOH (85 mL), and the mixture was subjected to an atmosphere of H2 overnight.

Workup

  1. customwas subjected to an atmosphere of H2 overnight

Sources & evidence

ORD record
ord-218a6519b0334d2ba39f9727fcbbbab7
Source dataset
uspto-grants-2012_03
Patent number
US08138340B2

Reaction notes

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