Phenol, 2-chloro-5-(trifluoromethyl)- → 7-{4-[3-(2-Chloro-5-trifluoromethylphenoxy)propyl]thiazol-2-yl}-6-[cyclopropyl-(2,3-dichlorobenzyl)carbamoyl]-3,9-diazabicyclo[3.3.1]non-6-ene-3,9-dicarboxylic acid di-tert-butyl ester

Participants

Role	Name	HCID	Charge
Reactant	Phenol, 2-chloro-5-(trifluoromethyl)-	HCID 123498	—
Reactant	6-[Cyclopropyl-(2,3-dichlorobenzyl)carbamoyl]-7-[4-(3-hydroxypropyl)thiazol-2-yl]-3,9-diazabicyclo[3.3.1]non-6-ene-3,9-dicarboxylic acid di-tert-butyl ester	HCID 68570774	—
Product	7-{4-[3-(2-Chloro-5-trifluoromethylphenoxy)propyl]thiazol-2-yl}-6-[cyclopropyl-(2,3-dichlorobenzyl)carbamoyl]-3,9-diazabicyclo[3.3.1]non-6-ene-3,9-dicarboxylic acid di-tert-butyl ester	HCID 86637072	—

This compound is prepared from compound E4 and 2-chloro-5-trifluoromethylphenol, according to the above-described procedure A.