HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-3,6-difluorophenol → 7-{2-[2-(2-Chloro-3,6-difluorophenoxy)ethoxy]thiazol-5-yl}-6-[cyclopropyl-(3-methoxy-2-methylbenzyl)carbamoyl]-3,9-diazabicyclo[3.3.1]non-6-ene-3,9-dicarboxylic acid di-tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-3,6-difluorophenol | HCID 2773561 | — |
| Reactant | 6-[Cyclopropyl-(3-methoxy-2-methylbenzyl)carbamoyl]-7-[2-(2-hydroxyethoxy)thiazol-5-yl]-3,9-diazabicyclo[3.3.1]non-6-ene-3,9-dicarboxylic acid di-tert-butyl ester | HCID 68570797 | — |
| Product | 7-{2-[2-(2-Chloro-3,6-difluorophenoxy)ethoxy]thiazol-5-yl}-6-[cyclopropyl-(3-methoxy-2-methylbenzyl)carbamoyl]-3,9-diazabicyclo[3.3.1]non-6-ene-3,9-dicarboxylic acid di-tert-butyl ester | HCID 69085915 | — |
Reaction Steps
This compound is prepared from compound E9 and 2-chloro-3,6-difluorophenol, according to the above-described procedure A. LC-MS: tR=1.22 min, ES+: 831.36.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08138340B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-cd61fca1219b4bc69004b4c5bc22b54c |
| Source note | uspto-grants-2012_03 |