Pyridine → HCID 57930904, compound

Participants

Reaction Steps

To a mixture of methyl 3,5-diethoxy-4-(1H-pyrazol-4-yl)benzoate (20 mg), cyclopropylboronic acid (24 mg) in THF (2 ml) were added Cu(OAc)2 (37 mg), pyridine (45 ul) and TEA (48 ul) at room temperature and irradiated with microwave at 120° C. for 15 min. After cooling to room temperature, the mixture was diluted with EtOAc, filtered through celite pad and the filtrate was evaporated under reduced pressure. The residue was purified by p-TLC (hexane/EtOAc) to give the title product as a colorless solid.

Provenance & Evidence