Ethanol → HCID 59547226, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of 3-aminobenzo[b]selenophene-2-carbonitrile (5.0 g) in aqueous sodium hydroxide solution (100 mL, 10%) was added ethanol (60 mL) and the mixture refluxed for 1 h. Ethanol was distilled off under vacuum (appr. 25 mL) and the mixture was allowed to cool to 5-10° C. The separated crystals were filtered off, washed with cold water and dried to give the product as a off-white color solid (3 g, 60%), mp 180-182° C. 1H NMR (400 MHz, DMSO-d6): δ 7.99-8.01 (1H, m, H-7), 7.92-7.94 (1H, m, H-4), 7.40-7.42 (2H, m, H-5,6), 7.21 (2H, s, —CONH2), 6.97 (2H, s, —NH2); LC-MS (positive ion mode): m/z 261, 263 (M+Na)+.

Provenance & Evidence