HCID 24765764, compound → HCID 24765763, compound

HRID 1097271Notes

Reaction equation

HRID 1097271 reaction equation
CN1C(=O)C(C)([N:9]2[C:17](=[O:18])[C:16]3[C:11](=[C:12]([F:22])[C:13]([F:21])=[C:14]([F:20])[C:15]=3[F:19])[C:10]2=[O:23])C(=O)NC1=O.Cl.[CH3:28][CH:29]1[C:34](=[O:35])[NH:33][C:32](=[O:36])[NH:31][C:30]1=[O:37].N[CH:39]1[C:44](=O)N(C(C)C)C(=O)N[C:40]1=O>>[CH:39]([N:31]1[C:30](=[O:37])[C:29]([CH3:28])([N:9]2[C:10](=[O:23])[C:11]3[C:16](=[C:15]([F:19])[C:14]([F:20])=[C:13]([F:21])[C:12]=3[F:22])[C:17]2=[O:18])[C:34](=[O:35])[NH:33][C:32]1=[O:36])([CH3:44])[CH3:40]

Participants

3

Reactant 2

HCID 24765764HCID 24765764, compoundHCID 66811050HCID 66811050, compound

Product 1

HCID 24765763HCID 24765763, compound

Procedure

Compound 19c was synthesized in the same manner as described for 19a from 5-amino-1-isopropylbarbituric-5-methylbarbituric acid hydrochloride (0.35 g, 1.50 mmol). The crude product was recrystallized from EtOH (70%) to give 1-isopropyl-5-methyl-5-(tetrafluorophthalimido)barbituric acid (19c) as white solid.

Workup

  1. customCompound 19c was synthesized in the same manner
  2. customThe crude product was recrystallized from EtOH (70%)

Sources & evidence

ORD record
ord-f89616180fb4421797d83913f9aae6f9
Source dataset
uspto-grants-2012_03
Patent number
US08143252B2

Reaction notes

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