HCID 24765764, compound → HCID 24765761, compound

HRID 1097272Notes

Reaction equation

HRID 1097272 reaction equation
CN1C(=O)C(C)(N2[C:17](=[O:18])[C:16]3[C:11](=[C:12]([F:22])[C:13]([F:21])=[C:14]([F:20])[C:15]=3[F:19])[C:10]2=[O:23])C(=O)NC1=O.Cl.[NH2:28][C:29]1([CH2:40][CH3:41])[C:34](=[O:35])[N:33]([CH2:36][CH3:37])[C:32](=[O:38])[NH:31][C:30]1=[O:39]>>[CH2:36]([N:33]1[C:34](=[O:35])[C:29]([CH2:40][CH3:41])([N:28]2[C:10](=[O:23])[C:11]3[C:16](=[C:15]([F:19])[C:14]([F:20])=[C:13]([F:21])[C:12]=3[F:22])[C:17]2=[O:18])[C:30](=[O:39])[NH:31][C:32]1=[O:38])[CH3:37]

Participants

3

Reactant 2

HCID 24765764HCID 24765764, compoundHCID 66811094HCID 66811094, compound

Product 1

HCID 24765761HCID 24765761, compound

Procedure

Compound 19d was synthesized in the same manner as described for 19a from 5-amino-1,5-diethylbarbituric acid hydrochloride (0.35 g, 1.50 mmol). The crude product was recrystallized from EtOH (70%) to give 1,5-diethyl-5-(tetrafluorophthalimido)barbituric acid (19d) as white crystals.

Workup

  1. customCompound 19d was synthesized in the same manner
  2. customThe crude product was recrystallized from EtOH (70%)

Sources & evidence

ORD record
ord-5722b3cc659147d8b6dfe62e217e535a
Source dataset
uspto-grants-2012_03
Patent number
US08143252B2

Reaction notes

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