HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-1-cyclohexyl-5-ethylbarbituric acid → N-(1-Cyclohexyl-5-ethyl-hexahydro-2,4,6-trioxo-5-pyrimidinyl)-2,3,4,5-tetrafluorobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-1-cyclohexyl-5-ethylbarbituric acid | HCID 15424936 | — |
| Reactant | N-(1-Ethyl-hexahydro-5-methyl-2,4,6-trioxo-5-pyrimidinyl)-2,3,4,5-tetrafluorobenzamide | HCID 24765666 | — |
| Product | N-(1-Cyclohexyl-5-ethyl-hexahydro-2,4,6-trioxo-5-pyrimidinyl)-2,3,4,5-tetrafluorobenzamide | HCID 24765664 | — |
Reaction Steps
Compound 20i was prepared by the same method described for 20f using 5-amino-1-cyclohexyl-5-ethylbarbituric acid (0.51 g, 2 mmol). The crude 1-cyclohexyl-5-ethyl-5-(tetrafluorobenzamido)barbituric acid (20i) was obtained as yellow crystals and did not require further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143252B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-6cc2f9e571234ef994b129593e09ffb4 |
| Source note | uspto-grants-2012_03 |