HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-5-ethyl-1-phenylbarbituric acid → N-(5-Ethyl-hexahydro-2,4,6-trioxo-1-phenyl-5-pyrimidinyl)-2,3,4,5-tetrafluorobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-5-ethyl-1-phenylbarbituric acid | HCID 15424937 | — |
| Reactant | N-(1-Ethyl-hexahydro-5-methyl-2,4,6-trioxo-5-pyrimidinyl)-2,3,4,5-tetrafluorobenzamide | HCID 24765666 | — |
| Product | N-(5-Ethyl-hexahydro-2,4,6-trioxo-1-phenyl-5-pyrimidinyl)-2,3,4,5-tetrafluorobenzamide | HCID 24765564 | — |
Reaction Steps
Compound 20k was prepared by the same method described for 20f using 5-amino-5-ethyl-1-phenylbarbituric acid (0.50 g, 2 mmol). The crude 5-ethyl-1-phenyl-5-(tetrafluorobenz-amido)barbituric acid (20k) was obtained as yellow crystals that were pure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143252B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-31fcb5f2b20d40d192ce55cbffc9c114 |
| Source note | uspto-grants-2012_03 |