3-Nitrobenzaldehyde → 3-Nitrobenzyl alcohol

Participants

Reaction Steps

To a solution of 3-nitrobenzaldehyde (5 g, 33.1 mmol) in MeOH (25 mL) at ambient temperature was added NaBH4 (1.25 g, 33.1 mmol) and the resulting mixture was stirred for 30 min. The reaction mixture was quenched with water. The product was extracted with CH2Cl2 thrice and the combined organic extracts were washed with H2O followed by brine, dried over Na2SO4 and concentrated under reduced pressure to furnish without purification 5 g of compound (xB). 1H NMR (CDCl3): δ 8.27 (s, 1H), 8.17 (dd, 1H), 7.73 (dd, 1H), 7.57 (t, 1H), 4.85 (s, 2H), 2.07 (s, 1H). MS (m/z): 154 [M+H]+.

Provenance & Evidence