HCID 25174615, compound → HCID 25174616, compound

HRID 1097305Notes

Reaction equation

HRID 1097305 reaction equation
[OH:1][CH2:2][CH2:3][NH:4][C:5](=[O:32])[C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[N:16][N:15]3[C:18]([C:21]4[CH:26]=[CH:25][CH:24]=[C:23]([N:27]5[CH:31]=[CH:30]C=N5)[CH:22]=4)=[CH:19][N:20]=[C:14]3[CH:13]=2)=[CH:8][CH:7]=1.C(O[C:36](=O)[C:37]1C=CC(C2C=NN3C(C4C=CN=C(C5C=CC=CC=5)C=4)=CN=C3C=2)=C[CH:38]=1)C>>[OH:1][CH2:2][CH2:3][NH:4][C:5](=[O:32])[C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[N:16][N:15]3[C:18]([C:21]4[CH:30]=[CH:31][N:27]=[C:23]([C:24]5[CH:38]=[CH:37][CH:36]=[CH:26][CH:25]=5)[CH:22]=4)=[CH:19][N:20]=[C:14]3[CH:13]=2)=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 25174615HCID 25174615, compoundHCID 25176705HCID 25176705, compound

Product 1

HCID 25174616HCID 25174616, compound

Procedure

This example is prepared by an analogous method to N-(2-Hydroxy-ethyl)-4-[3-(3-pyrazol-1-yl-phenyl)-imidazo-[1,2-b]-pyridazin-7-yl]-benzamide (Ex. 49) by replacing 4-[3-(3-Pyrazol-1-yl-phenyl)-imidazo[1,2-b]pyridazin-7-yl]-benzoic acid ethyl ester (Ex. 34) with 4-[3-(2-Phenylpyridin -4-yl)-imidazo[1,2-b]pyridazin-7-yl]-benzoic acid ethyl ester (Ex. 48).

Sources & evidence

ORD record
ord-2acdc7abda3b494dad2a55b8cf585af6
Source dataset
uspto-grants-2012_03
Patent number
US08143253B2

Reaction notes

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