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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1097337Generated: October 25, 2026

7-Chloro-5-[[(2,3-difluorophenyl)methyl]thio]-thiazolo[4,5-d]pyrimidin-2-amine → (+/-)-2-[2-[[2-Amino-5-[[(2,3-difluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]propoxy]ethanol

https://huagongshe.com/reaction/1097337

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Chloro-5-[[(2,3-difluorophenyl)methyl]thio]-thiazolo[4,5-d]pyrimidin-2-amineHCID 11221650—
Reactant(+/-)-2-[2-Aminopropoxy]ethanolHCID 55289290—
Product(+/-)-2-[2-[[2-Amino-5-[[(2,3-difluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]propoxy]ethanolHCID 86635797—

Reaction Steps

Prepared by the method of example 2 step a), using the product of example 4, step b) and (+/−)-2-[2-aminopropoxy]ethanol,

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143261B2
Source datasetuspto-grants-2012_03
ORD IDord-4392fe7b63ca42a195aa64cdf228d696
Source noteuspto-grants-2012_03