(2R)-2-Aminopropanamide hydrochloride → HCID 86635798, compound

HRID 1097338Notes

Reaction equation

HRID 1097338 reaction equation
Cl[C:2]1[C:3]2[S:20][C:19]([NH2:21])=[N:18][C:4]=2[N:5]=[C:6]([S:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([F:16])[C:11]=2[F:17])[N:7]=1.Cl.[NH2:23][C@H:24]([CH3:28])[C:25]([NH2:27])=[O:26]>>[NH2:21][C:19]1[S:20][C:3]2[C:2]([NH:23][C@H:24]([CH3:28])[C:25]([NH2:27])=[O:26])=[N:7][C:6]([S:8][CH2:9][C:10]3[CH:15]=[CH:14][CH:13]=[C:12]([F:16])[C:11]=3[F:17])=[N:5][C:4]=2[N:18]=1

Participants

3

Reactant 2

HCID 2775814(2R)-2-Aminopropanamide hydrochlorideHCID 112216507-Chloro-5-[[(2,3-difluorophenyl)methyl]thio]-thiazolo[4,5-d]pyrimidin-2-amine

Product 1

HCID 86635798HCID 86635798, compound

Procedure

Prepared by the method of example 2 step a), using the product of example 4, step b) and (2R)-2-amino-propanamide hydrochloride,

Workup

  1. customPrepared by the method of example 2 step a),

Sources & evidence

ORD record
ord-285bca961524429597e1197cede2f9f2
Source dataset
uspto-grants-2012_03
Patent number
US08143261B2

Reaction notes

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