Sodium Hydroxide → HCID 22671358, compound

HRID 1097344Notes

Reaction equation

HRID 1097344 reaction equation
C([S:4][CH2:5][C:6]1[CH:16]=[CH:15][C:9]([O:10][CH2:11][C:12]([NH2:14])=[O:13])=[C:8]([Cl:17])[CH:7]=1)(=O)C.[OH-].[Na+]>CO.O>[Cl:17][C:8]1[CH:7]=[C:6]([CH2:5][SH:4])[CH:16]=[CH:15][C:9]=1[O:10][CH2:11][C:12]([NH2:14])=[O:13]

Participants

5

Reactant 2

HCID 14798Sodium HydroxideHCID 22671278HCID 22671278, compound

Product 1

HCID 22671358HCID 22671358, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

To a solution of the product from example 15 step c) (1.0 g) in methanol (50 ml) was added sodium hydroxide pellets (0.15 g) and the mixture stirred for 2 days. The mixture was diluted with water and the subtitle compound collected by filtration. (0.7 g).

Workup

  1. filtrationthe subtitle compound collected by filtration

Sources & evidence

ORD record
ord-5c8554f6ac02481e9149362c22b77863
Source dataset
uspto-grants-2012_03
Patent number
US08143261B2

Reaction notes

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