HuagongsheHuagongshe Chemistry Print Report · For research reference only
9-Fluorenylmethyl chloroformate → HCID 86600020, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 9-Fluorenylmethyl chloroformate | HCID 34367 | — |
| Reactant | (2R)-2-Aminopropanamide hydrochloride | HCID 2775814 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Sodium Carbonate | HCID 10340 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86600020 | HCID 86600020 | 120.4% |
Reaction Steps
A solution of D-Alaninamide hydrochloride (3 g) in 10% sodium carbonate solution (50 ml) and dioxan (50 ml) was treated with FMOC chloride (6.24 g) in dioxane (40 ml) and allowed to stir overnight. The mixture was diluted with water (500 ml) and the product collected by filtration and dried in vacuo to give 9.0 g of the subtitle compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143261B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-472aa3422020432ab014d4559bf4dd0c |
| Source note | uspto-grants-2012_03 |