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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1097369Generated: October 26, 2026

7-Chloro-5-[[(2,3-difluorophenyl)methyl]thio]-thiazolo[4,5-d]pyrimidin-2-amine → (+/-)-2-[[2-Amino-5-[[(2,3-difluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-3-methoxy-1-propanol

https://huagongshe.com/reaction/1097369

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Chloro-5-[[(2,3-difluorophenyl)methyl]thio]-thiazolo[4,5-d]pyrimidin-2-amineHCID 11221650—
Reactant2-Amino-3-methoxypropan-1-ol hydrochlorideHCID 72996010—
Product(+/-)-2-[[2-Amino-5-[[(2,3-difluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-3-methoxy-1-propanolHCID 86635806—

Reaction Steps

Prepared by the method of example 12 step a) using the product of example 4 step b) and the product of example 40 step a).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143261B2
Source datasetuspto-grants-2012_03
ORD IDord-a7a272452bd24a1a939f081cabbcc7f9
Source noteuspto-grants-2012_03