HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Chloro-5-[[(2,3-difluorophenyl)methyl]thio]-thiazolo[4,5-d]pyrimidin-2-amine → (+/-)-2-[[2-Amino-5-[[(2,3-difluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-3-methoxy-1-propanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Chloro-5-[[(2,3-difluorophenyl)methyl]thio]-thiazolo[4,5-d]pyrimidin-2-amine | HCID 11221650 | — |
| Reactant | 2-Amino-3-methoxypropan-1-ol hydrochloride | HCID 72996010 | — |
| Product | (+/-)-2-[[2-Amino-5-[[(2,3-difluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-3-methoxy-1-propanol | HCID 86635806 | — |
Reaction Steps
Prepared by the method of example 12 step a) using the product of example 4 step b) and the product of example 40 step a).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143261B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-a7a272452bd24a1a939f081cabbcc7f9 |
| Source note | uspto-grants-2012_03 |