Serinol → 2-[[2-Amino-5-[(phenylmethyl)thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-1,3-propanediol

HRID 1097371Notes

Reaction equation

HRID 1097371 reaction equation
Cl[C:2]1[C:3]2[S:18][C:17]([NH2:19])=[N:16][C:4]=2[N:5]=[C:6]([S:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[N:7]=1.[NH2:20][CH:21]([CH2:24][OH:25])[CH2:22][OH:23]>>[NH2:19][C:17]1[S:18][C:3]2[C:2]([NH:20][CH:21]([CH2:24][OH:25])[CH2:22][OH:23])=[N:7][C:6]([S:8][CH2:9][C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)=[N:5][C:4]=2[N:16]=1

Participants

3

Reactant 2

HCID 68294SerinolHCID 112782745-(Benzylthio)-7-chloro[1,3]thiazolo[4,5-d]pyrimidin-2-amine

Product 1

HCID 226713402-[[2-Amino-5-[(phenylmethyl)thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-1,3-propanediol

Procedure

Prepared by the method of example 12 step a) using the product of example 1 step c) and 2-amino-1,3-propanediol.

Workup

  1. customPrepared by the method of example 12 step a)

Sources & evidence

ORD record
ord-92d65b3a38e34f34a0adeca3dceb757a
Source dataset
uspto-grants-2012_03
Patent number
US08143261B2

Reaction notes

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