Dimethyl Sulfoxide → 5-{9-(Cyclopropylmethyl)-8-[4-(methylsulfonyl)piperazin-1-yl]-6-morpholin-4-yl-9H-purin-2-yl}pyrimidin-2-amine
Reaction equation
[CH3:1][S:2](=[O:3])[CH3:4].[CH3:42][OH:43].[Cl:44][CH2:45][Cl:46].[Cl:5][c:6]1[n:7]([CH2:28][CH:29]2[CH2:30][CH2:31]2)[c:8]2[n:9][c:10](-[c:21]3[cH:22][n:23][c:24]([NH2:27])[n:25][cH:26]3)[n:11][c:12]([N:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[c:13]2[n:14]1.[S:32](=[O:33])(=[O:34])([CH3:35])[N:36]1[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]1>>[c:6]1([N:39]2[CH2:38][CH2:37][N:36]([S:32](=[O:33])(=[O:34])[CH3:35])[CH2:41][CH2:40]2)[n:7]([CH2:28][CH:29]2[CH2:30][CH2:31]2)[c:8]2[n:9][c:10](-[c:21]3[cH:22][n:23][c:24]([NH2:27])[n:25][cH:26]3)[n:11][c:12]([N:15]3[CH2:16][CH2:17][O:18][CH2:19][CH2:20]3)[c:13]2[n:14]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7ab81eed095146f3beb71e0011326439
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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