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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 10978Generated: October 26, 2026

3-benzyloxycarbonylamino-6-methyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic Acid → 6-benzyl-3-benzyloxycarbonylamino-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic Acid

https://huagongshe.com/reaction/10978

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-benzyloxycarbonylamino-6-methyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic AcidHCID 21979698—
Reactant6-benzyl-3-benzyloxycarbonylamino-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic Acid tert-butyl EsterHCID 69601014—
Product6-benzyl-3-benzyloxycarbonylamino-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic AcidHCID 2197969395.2%

Reaction Steps

According to the procedure for the preparation of intermediate 19b, intermediate 21a (149 mg, 0.313 mmol) was deproteted to afford 125 mg (95%) of intermediate 21b. MS (ESI) 420.4 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07094783B2
Source datasetuspto-grants-2006_08
ORD IDord-20c0265f8dc641c1a630eeba3226f3e7
Source noteuspto-grants-2006_08