HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(chloromethyl)-1-methyl-1H-1,2,3,4-tetrazole → 3-[2-Chloro-4-(1-methyl-1H-tetrazol-5-ylmethoxy)-phenyl]-1,1,1-trifluoro-2-(5-methyl-pyrazin-2-yl)-butan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(chloromethyl)-1-methyl-1H-1,2,3,4-tetrazole | HCID 12205086 | — |
| Reactant | 3-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(5-methyl-pyrazin-2-yl)-propyl]-phenol | HCID 57421231 | — |
| Product | 3-[2-Chloro-4-(1-methyl-1H-tetrazol-5-ylmethoxy)-phenyl]-1,1,1-trifluoro-2-(5-methyl-pyrazin-2-yl)-butan-2-ol | HCID 57421238 | — |
Reaction Steps
The title compound was prepared in analogy to Example 74 from 5-chloromethyl-1-methyl-1H-tetrazole [57235-84-4] and 3-chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(5-methyl-pyrazin-2-yl)-propyl]-phenol (Example 72). MS (m/e)=443.4 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143280B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-a46b5867a528409b9c4e11126ed9d87e |
| Source note | uspto-grants-2012_03 |