反应详情

In analogy to Example 183, 5-{2-[2-chloro-4-(4-fluoro-3-methoxy-phenoxy)-phenyl]-1-hydroxy-1-trifluoromethyl-propyl}-1-methyl-1H-pyridin-2-one (Example 199) was reacted with BBr3 to give the title compound as an off-white solid. MS (m/e)=472.2 [M+H+].