HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 5-[2-(4-bromo-2-chloro-phenyl)-propionyl]-1-methyl-1H-pyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 5-[2-(4-bromo-2-chloro-phenyl)-acetyl]-1-methyl-1H-pyridin-2-one | HCID 66699492 | — |
| Product | 5-[2-(4-bromo-2-chloro-phenyl)-propionyl]-1-methyl-1H-pyridin-2-one | HCID 66699419 | — |
Reaction Steps
In analogy to Example 1, steps 4 and 5, 5-[2-(4-bromo-2-chloro-phenyl)-acetyl]-1-methyl-1H-pyridin-2-one was alkylated with iodomethane to give 5-[2-(4-bromo-2-chloro-phenyl)-propionyl]-1-methyl-1H-pyridin-2-one which was further converted to the title compound. Colorless foam. MS (m/e, ISP neg. ion)=421.8 [M−H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143280B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-f1915d98437e40dca2592917779f62b7 |
| Source note | uspto-grants-2012_03 |