6-Methoxynicotinic acid → HCID 66699181, compound

HRID 1097972Notes

Reaction equation

HRID 1097972 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][N:4]=1.[Br:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19]Br)=[C:15]([Cl:21])[CH:14]=1>>[Br:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19][C:7]([C:6]2[CH:5]=[N:4][C:3]([O:2][CH3:1])=[CH:11][CH:10]=2)=[O:9])=[C:15]([Cl:21])[CH:14]=1

Participants

3

Reactant 2

HCID 5924996-Methoxynicotinic acidHCID 219144864-Bromo-1-(bromomethyl)-2-chlorobenzene

Product 1

HCID 66699181HCID 66699181, compound

Procedure

In analogy to Example 203, step 1, 6-methoxynicotinic acid was converted to the acid chloride and subsequently reacted with 4-bromo-1-bromomethyl-2-chloro-benzene to give the title compound (not completely pure) as a light yellow solid.

Sources & evidence

ORD record
ord-584ef20b9f344edca0ceabc8b3ce8998
Source dataset
uspto-grants-2012_03
Patent number
US08143280B2

Reaction notes

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