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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1097974Generated: October 31, 2026

Iodoethane → 5-[2-(4-Bromo-2-chloro-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1-ethyl-1H-pyridin-2-one

https://huagongshe.com/reaction/1097974

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethaneHCID 6340—
Reactant5-[2-(4-Bromo-2-chloro-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1H-pyridin-2-oneHCID 57421322—
Product5-[2-(4-Bromo-2-chloro-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1-ethyl-1H-pyridin-2-oneHCID 57421323—

Reaction Steps

In analogy to Example 195, 5-[2-(4-bromo-2-chloro-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1H-pyridin-2-one (Example 205) was alkylated with iodoethane to give the title compound as a light yellow oil. MS (m/e)=438.2 [M+H+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143280B2
Source datasetuspto-grants-2012_03
ORD IDord-c0c6c5e8ad414b199e6fbf88439acc58
Source noteuspto-grants-2012_03