5-Methylpyrazin-2-amine → HCID 57504591, compound

HRID 1098106Notes

Reaction equation

HRID 1098106 reaction equation
[Si:1]([O:8][C@@H:9]([CH2:13][O:14][CH3:15])[C:10]([OH:12])=O)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[CH3:16][C:17]1[N:18]=[CH:19][C:20]([NH2:23])=[N:21][CH:22]=1>>[Si:1]([O:8][C@@H:9]([CH2:13][O:14][CH3:15])[C:10]([NH:23][C:20]1[CH:19]=[N:18][C:17]([CH3:16])=[CH:22][N:21]=1)=[O:12])([C:4]([CH3:5])([CH3:6])[CH3:7])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 3132155-Methylpyrazin-2-amineHCID 57504586HCID 57504586, compound

Product 1

HCID 57504591HCID 57504591, compound

Procedure

C6a was prepared in an analogous fashion to C4d from (S)-2-(tert-butyldimethylsilyloxy)-3-methoxypropanoic acid C4c and 5-methylpyrazine-2-amine (CAS 5521-58-4).

Sources & evidence

ORD record
ord-aa4c9dd43bac445888c73db798c2a002
Source dataset
uspto-grants-2012_03
Patent number
US08143263B2

Reaction notes

Loading…