5-Amino-3-methyl-1,2,4-thiadiazole → HCID 57504595, compound

HRID 1098110Notes

Reaction equation

HRID 1098110 reaction equation
[Si:1]([O:8][C@@H:9]([CH2:13][O:14][CH:15]([CH3:17])[CH3:16])[C:10]([OH:12])=O)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[CH3:18][C:19]1[N:23]=[C:22]([NH2:24])[S:21][N:20]=1>>[Si:1]([O:8][C@@H:9]([CH2:13][O:14][CH:15]([CH3:17])[CH3:16])[C:10]([NH:24][C:22]1[S:21][N:20]=[C:19]([CH3:18])[N:23]=1)=[O:12])([C:4]([CH3:5])([CH3:6])[CH3:7])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 3506395-Amino-3-methyl-1,2,4-thiadiazoleHCID 57504592HCID 57504592, compound

Product 1

HCID 57504595HCID 57504595, compound

Procedure

C9a was prepared in an analogous fashion to C4d from (S)-2-(tert-butyldimethylsilyloxy)-3-isopropoxypropanoic acid C7c and 3-methyl-1,2,4-thiadiazol-5-amine.

Sources & evidence

ORD record
ord-7061828e819e421b86ebf87165e05d11
Source dataset
uspto-grants-2012_03
Patent number
US08143263B2

Reaction notes

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