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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1098116Generated: November 1, 2026

4-Chloro-1-(2-chlorophenyl)-1H-pyrazolo[3,4-D]pyrimidine → (2S)-methyl 2-(1-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)-3-isopropoxypropanoate

https://huagongshe.com/reaction/1098116

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-1-(2-chlorophenyl)-1H-pyrazolo[3,4-D]pyrimidineHCID 11265570—
Reactant(S)-methyl 2-hydroxy-3-isopropoxypropanoateHCID 59279510—
Product(2S)-methyl 2-(1-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)-3-isopropoxypropanoateHCID 59279536—

Reaction Steps

D2a was prepared in an analogous fashion to D1b from (S)-methyl 2-hydroxy-3-isopropoxypropanoate C7a and B1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143263B2
Source datasetuspto-grants-2012_03
ORD IDord-dcf0295646c5451a8d1e67a5cfd0d99c
Source noteuspto-grants-2012_03