HRID10983

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7864

Chloromethyl methyl ether

C2H5ClO

结构：CC(C)(C)OC(=O)[C@@H]1CCc2ncc(NC(=O)OCc3ccccc3)c(=O)n21

HCID54224046

未命名化合物

结构：CC(C)(C)OC(=O)C1(C)CCc2ncc(NC(=O)OCc3ccccc3)c(=O)n21

HCID69600879

未命名化合物

PRODUCTS

生成物

结构：COCC1(C(=O)OC(C)(C)C)CCc2ncc(NC(=O)OCc3ccccc3)c(=O)n21

HCID69600581

未命名化合物

收率 36%

PROCEDURE

实验过程

According to the procedure for the preparation of intermediate 19a, alkylation of intermediate 1g (250 mg, 0.649 mmol) with methoxymethylchloride afforded 101 mg (36%) of intermediate 23a. MS (ESI) 430.4 (M+H+), 452.4 (M+Na+).