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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1098396Generated: October 30, 2026

5-isopropenyl-1H-pyrrolo[2,3-b]pyridine → 5-isopropyl-1H-pyrrolo[2,3-b]pyridine

https://huagongshe.com/reaction/1098396

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-isopropenyl-1H-pyrrolo[2,3-b]pyridineHCID 58086810—
CatalystPalladium hydroxideHCID 9942167—
SolventTetrahydrofuranHCID 8028—
Product5-isopropyl-1H-pyrrolo[2,3-b]pyridineHCID 59928720—

Reaction Steps

To 5-isopropenyl-1H-pyrrolo[2,3-b]pyridine (98, 0.080 g, 0.501 mmol) in tetrahydrofuran (5.0 mL) was added 20% palladium hydroxide on carbon (5.0 mg). The reaction was stirred under hydrogen at 40 psi for 30 minutes. The reaction mixture was filtered and concentrated to give the compound (99, 0.078 g, 96%). MS (ESI) [M+H+]+=161.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143271B2
Source datasetuspto-grants-2012_03
ORD IDord-ef8cd681b1f441ffa7a2465b8d398a98
Source noteuspto-grants-2012_03