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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1098443Generated: November 1, 2026

HCID 59803850, compound → HCID 59803901, compound

https://huagongshe.com/reaction/1098443

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59803850HCID 59803850—
CatalystPalladium hydroxideHCID 9942167—
SolventMethanolHCID 887—
ProductHCID 59803901HCID 59803901—

Reaction Steps

To 3-(4-Benzyloxy-2,5-difluoro-benzyl)-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine (602, 0.70 g, 0.0014 mol) in methanol (30.0 mL) was added 50% palladium hydroxide on carbon (0.1 g) under an atmosphere of hydrogen. The reaction was stirred at room temperature overnight. The reaction was filtered and concentrated to give a colorless oil (603, 0.47 g, 82.0%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143271B2
Source datasetuspto-grants-2012_03
ORD IDord-fe4da85c07eb442e82e79b3a9c485794
Source noteuspto-grants-2012_03