Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1098497Generated: November 2, 2026

HCID 59506855, compound → HCID 58087581, compound

https://huagongshe.com/reaction/1098497

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59506855HCID 59506855—
CatalystPalladium hydroxideHCID 9942167—
SolventMethanolHCID 887—
ProductHCID 58087581HCID 58087581—

Reaction Steps

Benzyl-[4-(1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-phenyl]-amine (112, 210.0 mg, 0.447 mmol), methanol (15.0 mL) and palladium hydroxide (30.0 mg, 0.214 mmol) were combined. The reaction mixture was hydrogenated under an atmosphere of hydrogen (1 atm) at room temperature for 2 hours. Filtration and concentration gave the compound (113, 154 mg, 91%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143271B2
Source datasetuspto-grants-2012_03
ORD IDord-c5317893e3cb4a91a36c432a929e4992
Source noteuspto-grants-2012_03