HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → 5-methyl-1-(propan-2-yl)-1H-pyrazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 59734395 | HCID 59734395 | — |
| Product | 5-methyl-1-(propan-2-yl)-1H-pyrazole-4-carboxylic acid | HCID 23005671 | 70% |
Reaction Steps
In a procedure analogous to Example B6, ethyl 1-isopropyl-5-methyl-1H-pyrazole-4-carboxylate (537 mg, 2.74 mmol) and lithium hydroxide (459 mg, 10.95 mmol) were combined to give 1-isopropyl-5-methyl-1H-pyrazole-4-carboxylic acid (32 mg, 70% yield) as an off white solid. MS (ESI) m/z: 169.0 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143293B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-ed8bf95c61ac41e68dacb6720808edbe |
| Source note | uspto-grants-2012_03 |