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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1098739Generated: October 29, 2026

HCID 59253980, compound → 2-[4-(6-Hydroxyhexanoylamino)phenoxy]propionic acid methyl ester

https://huagongshe.com/reaction/1098739

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59253980HCID 59253980—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product2-[4-(6-Hydroxyhexanoylamino)phenoxy]propionic acid methyl esterHCID 59253943—

Reaction Steps

2-[4-(6-Benzyloxyhexanoylamino)-phenoxy]-propionic acid methyl ester 59 (15 g, 37.59 mmol) was dissolved in methanol (150 ml) in a pressure vessel. Palladium on carbon (50% wet, 5%, 15 g) was added and the mixture stirred under hydrogen atmosphere (4 kg) for 16 hrs. Catalyst was removed by filtration and methanol distilled off.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143325B2
Source datasetuspto-grants-2012_03
ORD IDord-ccb0063acca747e78cc9365c7cb04734
Source noteuspto-grants-2012_03