HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59253980, compound → 2-[4-(6-Hydroxyhexanoylamino)phenoxy]propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59253980 | HCID 59253980 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-[4-(6-Hydroxyhexanoylamino)phenoxy]propionic acid methyl ester | HCID 59253943 | — |
Reaction Steps
2-[4-(6-Benzyloxyhexanoylamino)-phenoxy]-propionic acid methyl ester 59 (15 g, 37.59 mmol) was dissolved in methanol (150 ml) in a pressure vessel. Palladium on carbon (50% wet, 5%, 15 g) was added and the mixture stirred under hydrogen atmosphere (4 kg) for 16 hrs. Catalyst was removed by filtration and methanol distilled off.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143325B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-ccb0063acca747e78cc9365c7cb04734 |
| Source note | uspto-grants-2012_03 |