Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1098871Generated: November 1, 2026

(1R,2S)-2-amino-1-phenylbutan-1-ol hydrochloride → (1R,2S)-1-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-phenylbutan-2-amine

https://huagongshe.com/reaction/1098871

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1R,2S)-2-amino-1-phenylbutan-1-ol hydrochlorideHCID 12562408—
Reactant(1R,2S)-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-phenylpentan-2-amineHCID 59339774—
Product(1R,2S)-1-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-phenylbutan-2-amineHCID 59339729—

Reaction Steps

was synthesised in the same way as (91a) from (1R,2S)-2-amino-1-phenylbutan-1-ol hydrochloride (95b, 53 mg, 0.26 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143290B2
Source datasetuspto-grants-2012_03
ORD IDord-b01c9dc5b58d46a994debdc5f076268e
Source noteuspto-grants-2012_03