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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1098875Generated: November 1, 2026

(1R,2S)-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-phenylpentan-2-amine → (1R,2S)-1-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-(3-methoxyphenyl)butan-2-amine

https://huagongshe.com/reaction/1098875

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1R,2S)-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-phenylpentan-2-amineHCID 59339774—
Reactant(1R,2S)-2-amino-1-(3-methoxyphenyl)butan-1-ol hydrochlorideHCID 66812819—
Product(1R,2S)-1-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-(3-methoxyphenyl)butan-2-amineHCID 59339801—

Reaction Steps

was synthesised in the same way as (91a) from (1R,2S)-2-amino-1-(3-methoxyphenyl)butan-1-ol hydrochloride (97b, 50 mg, 0.22 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143290B2
Source datasetuspto-grants-2012_03
ORD IDord-4ec03f09dd6e4aafadff4c5cfdc10c54
Source noteuspto-grants-2012_03