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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1098972Generated: November 2, 2026

4,5-dimethylthiophene-2-carboxylic acid → HCID 59339725, compound

https://huagongshe.com/reaction/1098972

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,5-dimethylthiophene-2-carboxylic acidHCID 2769634—
Reactant(1R,2S)-1-(1-(4-fluorophenyl)indazol-5-yloxy)-1-(3-methoxyphenyl)propan-2-amineHCID 59339733—
ProductHCID 59339725HCID 59339725—

Reaction Steps

Prepared as described in Example 269 from (1R,2S)-1-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-(3-methoxyphenyl)propan-2-amine (6a, 50 mg, 0.13 mmol) and 4,5-dimethylthiophene-2-carboxylic acid (23 mg, 0.15 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143290B2
Source datasetuspto-grants-2012_03
ORD IDord-9bd7210da39a40bca63374ee6f699b6d
Source noteuspto-grants-2012_03