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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1098983Generated: November 1, 2026

1-((Tert-butoxy)carbonyl)pyrrolidine-3-carboxylic acid → HCID 59436132, compound

https://huagongshe.com/reaction/1098983

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-((Tert-butoxy)carbonyl)pyrrolidine-3-carboxylic acidHCID 2760529—
Reactant(1R,2S)-1-(1-(4-fluorophenyl)indazol-5-yloxy)-1-(3-methoxyphenyl)propan-2-amineHCID 59339733—
ProductHCID 59436132HCID 59436132—

Reaction Steps

Prepared as described in Example 83 using (1R,2S)-1-(1-(4-fluorophenyl)-1H-indazol-5-yloxy)-1-(3-methoxyphenyl)propan-2-amine (6a, 50 mg, 0.13 mmol) and 1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid (37 mg, 0.17 mmol). Yield 38 mg (50%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143290B2
Source datasetuspto-grants-2012_03
ORD IDord-da5d25ddbf4c4ee388e4657b690974d4
Source noteuspto-grants-2012_03