HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1099055Generated: October 31, 2026
Hydrazine hydrate (1:1) → 6-(4-Bromo-3-fluorophenyl)-3-hydrazino-1,2,4-triazine
https://huagongshe.com/reaction/1099055
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 6-(4-Bromo-3-fluorophenyl)-3-(methylthio)-1,2,4-triazine | HCID 66813112 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-(4-Bromo-3-fluorophenyl)-3-hydrazino-1,2,4-triazine | HCID 59216302 | 77.7% |
Reaction Steps
A mixture of 6-(4-bromo-3-fluorophenyl)-3-(methylthio)-1,2,4-triazine (1.15 g, 0.00383 mol) and hydrazine hydrate (0.74 mL, 0.015 mol) in ethanol (50 mL) was heated at 90° C. for 20 h. After cooling, the formed precipitate was collected by filtration, and dried in-vacuo to afford the desired product (0.845 g, 77.6%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08143251B2 |
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| Source dataset | uspto-grants-2012_03 |
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| ORD ID | ord-d623b7ae670348988d239b3d7b872548 |
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| Source note | uspto-grants-2012_03 |
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