Acetic Acid → HCID 86230360, compound

HRID 1099127Notes

Reaction equation

HRID 1099127 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([O:10][C:11]2[CH:16]=[CH:15][C:14]([CH2:17][OH:18])=[CH:13][CH:12]=2)=[N:8][CH:9]=1)([O-])=O.C(O)(=O)C.[CH3:23][S:24](Cl)(=[O:26])=[O:25]>N1C=CC=CC=1.[Zn].[O-2].[O-2].[Mn+4]>[CH:17]([C:14]1[CH:15]=[CH:16][C:11]([O:10][C:7]2[N:8]=[CH:9][C:4]([NH:1][S:24]([CH3:23])(=[O:26])=[O:25])=[CH:5][CH:6]=2)=[CH:12][CH:13]=1)=[O:18]

Participants

7

Reactant 3

HCID 176Acetic AcidHCID 31297Methanesulfonyl chlorideHCID 17604338HCID 17604338, compound

Product 1

HCID 86230360HCID 86230360, compound

Reagents, catalysts & solvents 3

HCID 23994ZincCatalystHCID 178418406HCID 178418406, compoundCatalystHCID 1049PyridineSolvent

Procedure

{4-[(5-nitropyridin-2-yl)oxy]phenyl}methanol was subjected to reduction of nitro group by using zinc and acetic acid, the obtained compound reacted with methanesulfonyl chloride in pyridine, and the obtained compound was subjected to oxidation by using manganese dioxide to give the title compound having the following physical data.

Sources & evidence

ORD record
ord-d8ac546367024d60b8b549ef860dd388
Source dataset
uspto-grants-2012_03
Patent number
US08143404B2

Reaction notes

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