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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1099198Generated: November 2, 2026

Trifluoroacetic acid methylene chloride → HCID 86639103, compound

https://huagongshe.com/reaction/1099198

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acid methylene chlorideHCID 21863450—
ReactantHCID 66811489HCID 66811489—
ProductHCID 86639103HCID 8663910391%

Reaction Steps

A solution of tert-butyl 2-[(benzylamino)carbonyl]-3-phenylpiperidine-1-carboxylate (1.44 g, 3.65 mmol) in 1:1 TFA/dichloromethane (10 ml) was allowed to stir for 3 h. The reaction was concentrated in vacuo, and the residue was dissolved in acetonitrile/water and lyophilized to yield 2-[(benzylamino)carbonyl]-3-phenylpiperidinium trifluoroacetate (91%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143405B2
Source datasetuspto-grants-2012_03
ORD IDord-1583fb9a72cb440997756f85941e3782
Source noteuspto-grants-2012_03