HCID 66811607, compound → HCID 66811231, compound

Participants

Reaction Steps

To a solution of tert-butyl 2-(5-{1-[(benzyloxy)carbonyl]azetidin-3-yl}-1,3,4-oxadiazol-2-yl)-3-phenylpiperidine-1-carboxylate (200 mg, 0.39 mmol) in ethanol (10 ml) was added 10% palladium on carbon (20.0 mg). The reaction was charged with 1 atm hydrogen gas and allowed to stir for 1 h. The reaction was filtered through celite, and the filtrate was concentrated to yield tert-butyl 2-(5-azetidin-3-yl-1,3,4-oxadiazol-2-yl)-3-phenylpiperidine-1-carboxylate (100%). LCMS (M+H)=385.2.

Provenance & Evidence