HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinemethanol → 6-(3-Pyridinylmethoxy)-3-pyridinecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinemethanol | HCID 7510 | — |
| Reactant | Ethyl 6-chloronicotinate | HCID 2799611 | — |
| Product | 6-(3-Pyridinylmethoxy)-3-pyridinecarboxylic acid | HCID 59354909 | 66% |
Reaction Steps
The title compound was synthesized as described for Intermediate example I-92 in 66% yield starting from ethyl 6-chloronicotinate and pyridine-3-methanol; 1H NMR (400 MHz, DMSO-d6) δ ppm 8.67-8.76 (m, 2 H), 8.54 (d, 1 H), 8.17 (dd, 1 H), 7.89 (d, 1 H), 7.42 (dd, 1 H), 6.98 (d, 1 H), 5.47 (s, 2 H); (APPI/APCI) m/z 231[M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143408B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-1415e6f7f4b8426c9208873641facd5f |
| Source note | uspto-grants-2012_03 |