HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylparaben → N-[4-(Cyclobutylmethoxy)benzoyl]glycine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylparaben | HCID 7456 | — |
| Reactant | Cyclobutylcarbinol | HCID 78130 | — |
| Reactant | N-[4-(2-Cyclopropylethoxy)benzoyl]glycine | HCID 66812105 | — |
| Product | N-[4-(Cyclobutylmethoxy)benzoyl]glycine | HCID 66812262 | 97% |
Reaction Steps
The same reactions as in Example 9 (9a) and (9b) were conducted using methyl 4-hydroxybenzoate (3.81 g, 25.0 mmol) and cyclobutylmethanol (2.36 mL, 25.0 mmol) to give 6.41 g of the title compound (colorless oil, yield: 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143446B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-3b6347393dd04806b435ff94e543f214 |
| Source note | uspto-grants-2012_03 |