HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylparaben → 2-(4-(2-(Thiophen-2-yl)ethoxy)benzamido)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylparaben | HCID 7456 | — |
| Reactant | 2-Thiopheneethanol | HCID 79400 | — |
| Reactant | N-[4-(2-Cyclopropylethoxy)benzoyl]glycine | HCID 66812105 | — |
| Product | 2-(4-(2-(Thiophen-2-yl)ethoxy)benzamido)acetic acid | HCID 66812445 | 65% |
Reaction Steps
The same reactions as in Example 9 (9a) and (9b) were conducted using methyl 4-hydroxybenzoate (1.55 g, 10.2 mmol) and 2-(2-thienyl)ethanol (1.20 mL, 10.8 mmol) to give 2.02 g of the title compound (white powder, yield: 65%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143446B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-f7731aecc9b94211aa53393328206217 |
| Source note | uspto-grants-2012_03 |